范克龙课题组

简 历：

　2012-2016 武汉大学，生命科学学院，学士

　2016-2021 中国科学院生物物理研究所，博士

　2021-至今 中国科学院生物物理研究所，博士后

获奖及荣誉：

　1.2016年度“中国科学院大学三好学生”

　2.2016年度“中国科学院大学新生奖学金”

　3.2017年度“中国科学院大学优秀共青团员”

　4.2018年度“中国科学院大学三好学生”

　5.2018年度“硕士研究生国家奖学金”

　6.2020年度“博士研究生国家奖学金”

社会任职：

研究方向：

　 纳米酶的机制解析及生物医学应用研究

承担项目情况：

代表论著：

　1.Juqun Xi#,Ruofei Zhang#, Liming Wang, Wei Xu, Qian Liang, Jingyun Li, Jian Jiang, Yili Yang, Xiyun Yan, Kelong Fan. A nanozyme‐based artificial peroxisome ameliorates hyperuricemia and ischemic stroke [J].Advanced Functional Materials, 2021, 31(9): 2007130. (IF = 18.808)

　2.Zhuoran Wang#, Ruofei Zhang#, Xiyun Yan, Kelong Fan. Structure and activity of nanozymes: Inspirations for de novo design of nanozymes [J].Materials Today, 2020, 41: 81-119. (IF = 31.041)

　3.Ruofei Zhang, Yunlong Zhou, Xiyun Yan, Kelong Fan. Advances in chiral nanozymes: a review [J].Microchimica Acta, 2019, 186(12): 1-12. (IF = 5.833)

　4.Ruofei Zhang, Kelong Fan, Xiyun Yan. Nanozymes: created by learning from nature [J].Science China Life Sciences, 2020, 1-18. (IF = 6.038, ESI高被引)

　5.Ruofei Zhang, Xiyun Yan, Kelong Fan. Nanozymes Inspired by Natural Enzymes [J].Accounts of Materials Research, 2021. DOI: 10.1021/accountsmr.1c00074. (ACS editor’s choice)

　6.Hanqing Zhao#,Ruofei Zhang#, Xiyun Yan, Kelong Fan. Superoxide dismutase nanozymes: an emerging star for anti-oxidation [J]. Journal of Materials Chemistry B, 2021. DOI: 10.1039/D1TB00720C.( IF = 6.331, Hot papers)

　7.Ruofei Zhang, Kelong Fan, Xiyun Yan. Cerium Oxide Based Nanozymes [M]//YAN X.Nanozymology: Connecting Biology and Nanotechnology. Singapore; Springer Singapore. 2020: 279-329.

　8.Ruofei Zhang, Xiyun Yan, Kelong Fan. The Advances of Nanozyme in Brain Disease [M]//XUE X.Nanomedicine in Brain Diseases: Principles and Application. Singapore; Springer Singapore. 2019: 139-79.

　9.Bing Jiang,Ruofei Zhang, Jianlin Zhang, Yaxin Hou, Xuehui Chen, Meng Zhou, Xiuyun Tian, Chunyi Hao, Kelong Fan, Xiyun Yan. GRP78-targeted ferritin nanocaged ultra-high dose of doxorubicin for hepatocellular carcinoma therapy [J].Theranostics, 2019, 9(8): 2167-82. (IF = 11.556)

　10.Yanan Zhang, Yingni Li, Jianlin Zhang, Xuehui Chen,Ruofei Zhang, Guoming Sun, Bing Jiang, Kelong Fan, Zhanguo Li, Xiyun Yan. Nanocage-Based Capture-Detection System for the Clinical Diagnosis of Autoimmune Disease [J].Small, 2021, 17(25): 2101655. (IF = 13.281)

　11.Zhuoran Wang, Shuai Zhang,Ruofei Zhang, Xuehui Chen, Guoming Sun, Meng Zhou, Qiubai Han, Baoli Zhang, Yue Zhao, Bing Jiang, Yili Yang, Xiyun Yan, Kelong Fan. Bioengineered Dual-Targeting Protein Nanocage for Stereoscopically Loading of Synergistic Hydrophilic/Hydrophobic Drugs to Enhance Anticancer Efficacy [J].Advanced Functional Materials, n/a(n/a): 2102004. (IF = 18.808)

　12.Shufang Ji, Bing Jiang, Haigang Hao, Yuanjun Chen, Juncai Dong, Yu Mao, Zedong Zhang, Rui Gao, Wenxing Chen,Ruofei Zhang, Qian Liang, Haijing Li, Shuhu Liu, Yu Wang, Qinghua Zhang, Lin Gu, Demin Duan, Minmin Liang, Dingsheng Wang, Xiyun Yan, Yadong Li. Matching the kinetics of natural enzymes with a single-atom iron nanozyme [J].Nature Catalysis, 2021, 4(5): 407-17. (IF = 41.813)

　13.Shuqi Wu, Yang Li,Ruofei Zhang, Kelong Fan, Weihang Ding, Letong Xu, Lianbing Zhang. Persistent luminescence-polypyrrole nanocomposite for dual-modal imaging and photothermal therapy of mammary cancer [J].Talanta, 2021, 221: 121435. (IF = 6.057)

　14.Qian Liang, Juqun Xi, Xuejiao J. Gao,Ruofei Zhang, Yili Yang, Xingfa Gao, Xiyun Yan, Lizeng Gao, Kelong Fan. A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy [J].Nano Today, 2020, 35:100935. (IF = 20.722)

　15.Xiaohua Jia, Kelong Fan,Ruofei Zhang, Dan Zhang, Jianjun Zhang, Yuan Gao, Tao Zhang, Wanjun Li, Junlai Li, Xiyun Yan, Jie Tian. Precise visual distinction of brain glioma from normal tissues via targeted photoacoustic and fluorescence navigation [J].Nanomedicine: Nanotechnology, Biology and Medicine, 2020, 27: 102204. (IF = 6.458)

　16.Yaxin Hou,Ruofei Zhang, Xiyun Yan, Kelong Fan. Nanozymes: a new choice for disease treatment [J].SCIENTIA SINICA Vitae, 2020, 50(1674-7232): 311.