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2009年前代表性论文

Lee S,Deng H*,Yu F, Melega WP, Damoiseaux R, Bradley KA, Sun R.Regulation of KSHV Reactivation by Dopamine Receptor-Mediated Signaling Pathways.J Acquir Immune Defic Syndr.2008 Aug 15;48(5):531-40. doi: 10.1097/QAI.0b013e31817fbdcf. (*Co-Correspondingauthors)

Benach J, Wang L, Chen Y, Ho CK, Lee S, Seetharaman J, Xiao R, Acton TB, Montelione GT,DengH, Sun R, Tong L.Structural and functional studies of the abundant tegument proteinORF52 frommurine gammaherpesvirus-68.J Biol Chem. 2007 Oct 26;282(43):31534-41. Epub 2007 Aug 15.

Bortz E, Wang L, Jia Q, Wu TT, Whitelegge JP,Deng H, Zhou ZH, Sun R.Murine Gammaherpesvirus-68 ORF52 Encodes a Tegument Protein Required for Virion Morphogenesis in the Cytoplasm.J Virol. 2007 Sep;81(18):10137-50. Epub 2007 Jul 18.

Wong E, Wu TT, Reyes N,Deng H, Sun R.Murine gammaherpesvirus 68 open reading frame 24 is required for late gene expression after DNA replication.J Virol.2007 Jun;81(12):6761-4. Epub 2007 Mar 28.

Yu F, Harada JN, Brown HJ,Deng H, Song MJ, Wu TT, Kato-Stankiewicz J, Nelson CG, Vieira J, Tamanoi F, Chanda SK, Sun R.Systematic identification of cellular signals reactivating Kaposi’sarcoma-associated herpesvirus.PLoS Pathog. 2007 Mar;3(3):e44.doi:10.1371/journal.ppat.0030044. Epub 2007 Mar 30.

Deng H, Liang Y, Sun R.Regulation of KSHV lytic gene expression.Curr Top Microbiol Immunol. 2007;312:157-83. (Invited review)

Arumugaswami V, Wu TT, Martinez-Guzman D, Jia Q,Deng H, Reyes N, Sun R.ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirus.J Virol. 2006 Oct;80(19):9730-40.doi: 10.1128/JVI.00246-06

Chang M, HJ Brown, TL Symensma, L. Tanaka, JM Arevalo, A. Collado-Hidalgo, Z. Galic,Deng H, JA Zack, R. Sun, and SW Cole.Activation of HHV-8 lytic replication by ?-adrenoreceptors: PKA-dependent control of RTA expression and trans-activating capacity.J Virol. 2005 Nov; 79(21): 13538-47.doi: 10.1128/JVI.79.21.13538-13547.2005

Rickabaugh TM, Brown HJ, Wu TT, Song MJ, Hwang S,Deng H, Mitsouras K, Sun R.Kaposi’s sarcoma-associated herpesvirus/human herpesvirus 8 reactivates murine gammaherpesvirus 68 from latency.J Virol. 2005 Mar;79(5):3217-22.doi: 10.1128/JVI.79.5.3217-3222.

Deng H*,Chu JT, Park NH, Sun R.Identification of cis-sequences required for lytic replication and packaging of murine gammaherpesvirus-68.J Virol. 2004 Sep;78(17):9123-31. (*Corresponding author)

Zhu J, Trang P, Kim K, Zhou T,Deng H, Liu F.Effective inhibition of Rta expression and lytic replication of Kaposi’s sarcoma-associated herpesvirus by human RNase P.Proc Natl Acad Sci U S A.2004 Jun 15;101(24):9073-8. Epub 2004 Jun 7.

Song MJ,Deng H, Sun R. Sun.Comparative study of regulation of RTA-responsive genes in Kaposi’s sarcoma-associated herpesvirus/human herpesvirus 8.J Virol.2003 Sep;77(17):9451-62.

Brown HJ, Song MJ,Deng H, Wu TT, Cheng G, and Sun R.Gammaherpesviruses replication is regulated by NF-kappaB.J Virol. 2003 77:8532-8540.

Deng H, Song MJ, Chu JT, Sun R.Transcriptional regulation of the interleukin-6 gene encoded by human herpesvirus 8/Kaposi’s sarcoma-associated herpesvirus.J Virol. 2002 Aug;76(16):8252-64.

Deng H, Chu JT, Rettig MB, Martinez-Maza O, Sun R.Rta of the human herpesvirus 8/Kaposi’s sarcoma-associated herpesvirus up-regulates human interleukin-6 gene expression.Blood. 2002 Sep 1;100(5):1919-21.

Varthakavi V, Smith RM,Deng H, Sun R, Spearman P.Human Immunodeficiency Virus Type-1 Activates Lytic Cycle Replication of Kaposi's Sarcoma-Associated Herpesvirus through Induction of KSHV Rta.Virology. 2002 Jun 5;297(2):270-80.

Deng H, Young A, Sun R.Auto-activation of the rta gene of human herpesvirus 8/Kaposi’s sarcoma-associated herpesvirus.J Gen Virol. 2000 Dec;81(Pt 12):3043-8.

Greenberg RA, O'Hagan RC,Deng H, Xiao Q, Hann SR, Adams RR, Lichtsteiner S, Chin L, Morin GB, DePinho RA.Telomerase reverse transcriptase is a direct target of c-Myc but is not functionally equivalent in cellular transformation.Oncogene. 1999 Feb 4;18(5):1219-26.

Deng H, Dewhurst S.Functional identification and analysis of cis-acting sequences which mediate genome cleavage and packaging in human herpesvirus 6.J Virol.1998 Jan;72(1):320-9.

Bulboaca, GH,Deng H,Dewhurst S. and Calos MP. Telomeric sequences from human herpesvirus 6 do not mediate nuclear retention of episomal DNA in human cells.Arch Virol. 1998;143(3):563-70.

van Loon N, Dykes C,Deng H, Dominguez G, Nicholas J, Dewhurst S.Identification and analysis of a lytic phase origin of DNA replication in human herpesvirus 7.J Virol. 1997 Apr;71(4):3279-84.

Secchiero P, Nicholas J,Deng H, Xiaopeng T, van Loon N, Ruvolo VR, Berneman ZN, Reitz MS Jr, Dewhurst S.Identification of human telomeric repeat motifs at the genome termini of human herpesvirus 7: structural analysis and heterogeneity.J Virol. 1995 Dec;69(12):8041-5.

(*Co-Corresponding authors)

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