2014 Chen Y, Wang S, Yi Z, Tian H, Aliyari S, Li Y, Chen G, Liu P, Zhong J, Chen X, Du P, Su L, Qin FX,Deng H*,Cheng G*.Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms.Sci Rep.2014 Dec 3; 4:7242. doi: 10.1038/srep07242. Epub 2014 Dec 3. Wong-Ho E, Wu TT, Davis ZH, Zhang B, Huang J, Gong H,Deng H,Liu F, Glaunsinger B, Sun R.Unconventional Sequence Requirement for Viral Late Gene Core Promoters of Murine Gammaherpesvirus 68.J Virol, 2014 Mar;88(6):3411-22. doi: 10.1128/JVI.01374-13. Epub 2014 Jan 8. Shen S, Guo H, andDeng H*.Murine gammaherpesvirus-68 ORF38 encodes a tegument protein and is packaged into virions during secondary envelopment.Protein Cell. 2014 Feb;5(2):141-50.doi: 10.1007/s13238-013-0005-0. Epub 2014 Jan 29. 2013 Duarte M, Wang L, Calderwood MA, Adelmant G, Ohashi M, Roecklein-Canfield J, Marto JA, Hill DE,Deng H,Johannsen E. An RS Motif within the Epstein-Barr Virus BLRF2 Tegument Protein Is Phosphorylated by SRPK2 and Is Important for Viral Replication.PLoS One. 2013;8(1):e53512. doi: 10.1371/journal.pone.0053512.Epub 2013 Jan 9. Xuan Y, Gong D, Qi J, Han C,Deng H*,Gao G*.ZAP inhibits murine gammaherpesvirus-68 ORF64 expression and is antagonized by RTA.J Virol, 2013 Mar;87(5):2735-43.doi: 10.1128/JVI.03015-12. Epub 2012 Dec 19. 2012 Xuan Y, Liu L, Shen S,Deng H*,Gao G*.Zinc-finger antiviral protein inhibits murine gammaherpesvirus-68 M2 expression and regulates viral latency in cultured cells.J Virol, 2012 Nov;86(22):12431-4.doi: 10.1128/JVI.01514-12. Epub 2012 Sep 5. Sun Q, Han C, Liu L, Wang Y,Deng H,Bai L, Jiang T.Crystal structure and functional implication of the RUN domain of human NESCA.Protein Cell.2012 Aug;3(8):609-17. doi: 10.1007/s13238-012-2052-3. Epub 2012 Jul 22. Wang L, Guo H, Reyes N, Lee S, Bortz E, Guo F, Sun R, Tong L,Deng H*.DistinctDomains in ORF52 Tegument Protein Mediate Essential Functions in Murine Gammaherpesvirus 68 Virion Tegumentation and Secondary Envelopment.J Virol, 2012 Feb;86(3):1348-57. doi: 10.1128/JVI.05497-1. Epub 2011 Nov 16. Noh CW, Cho HJ, Kang HR, Jin HY, Lee S,Deng H, Wu TT, Arumugaswami V, Sun R, Song MJ.The Virion-Associated Open Reading Frame 49 of Murine Gammaherpesvirus 68 Promotes Viral Replication both In Vitro and In Vivo as a Derepressor of RTA.J Virol. 2012 Jan;86(2):1109-18.doi: 10.1128/JVI.05785-1.Epub 2011 Nov 16. 2011 Lee S, Salwinski L, Zhang C, Chu D, Sampankanpanich C, Reyes NA, Vangeloff A, Xing F, Li X, Wu T, Sahasrabudhe S,Deng H, LaCount DJ, Sun R.An Integrated Approach to Elucidate the Intra-Viral and Viral-Cellular Protein Interaction Networks of a Gamma-Herpesvirus.PLoS Pathog7(10): e1002297. doi:10.1371/journal.ppat.1002297, 2011. Epub 2011 Oct 20. Hong Y, Qi J, Gong D, Han C,Deng H*.Replication and Transcription Activator of Murine Gammaherpesvirus-68 Binds to An RTA-responsive Element and Activates the Expression of ORF18.J Virol, 2011 Nov;85(21):11338-50.doi: 10.1128/JVI.00561-11. Epub 2011 Aug 17. Qi J, Gong D, andDeng H*.CCAAT/enhancer binding proteins play a role in oriLyt dependent genome replication during murine gammaherpesvirus 68 (MHV-68) de novo infection.Protein Cell, 2011 Jun; 2(6):463-9.doi: 10.1007/s13238-011-1060-z. Epub 2011 Jul 12. Ding X, Yang W, Shi X, Du P, Su L, Qin Z, Chen J,Deng H*.Tumor Necrosis Factor Receptor 1 Mediates Dendritic Cell Maturation and CD8 T Cell Response through Two Distinct Mechanisms.J Immunol. 2011 Aug 1;187(3):1184-91. doi: 10.4049/jimmunol.1002902. Epub 2011 Jun 27. Cao Y, Koh X, Dong L, Du X, Wu A, Ding X,Deng H, Shu Y, Chen J, Jiang T.Rapid Estimation of Binding Activity of Influenza Virus Hemagglutinin to Human and Avian Receptors.PLoS One6(4): e18664. doi:10.1371/journal.pone.0018664.Epub 2011 Apr 13. Hong Y, Qi J, Gong D, Deng J,Deng H*.Identification of an RTA Responsive Element in Murine Gammaherpesvirus-68 Genome.Progress in Biochemistry and Biophysics.2011;38:936-944. Yang W, Ding X, Deng J, Lu Y, Matsuda Z, Thiel A, Chen J,Deng H*,Qin Z*.Interferon-gamma negatively regulates Th17-mediated immunopathology during mouse hepatitis virus infection.J Mol Med. 2011 Apr;89(4):399-409. doi: 10.1007/s00109-010-0711-5. Epub 2010 Dec 30. 2010 Guo H, Shen S, Wang L,Deng H*.Role of tegument proteins in herpesvirus assembly and egress.Protein Cell. 2010 Nov;1(11):987-98.doi: 10.1007/s13238-010-0120-0. Epub 2010 Dec 10.(Invited review) Li X, Chen S, Feng J,Deng H, Sun R.Myc Is Required for the Maintenance of Kaposi's Sarcoma-Associated Herpesvirus Latency.J Virol. 2010 Sep;84(17):8945-8. doi: 10.1128/JVI.00244-10. Epub 2010 Jun 23. Li X, Feng J, Chen S, Peng L, He WW, Qi J,Deng H, Sun R.Tpl2/AP-1 Enhances Murine Gammaherpesvirus 68 Lytic Replication.J Virol. 2010 Feb;84(4):1881-90. doi: 10.1128/JVI.01856-09. Epub 2009 Nov 25. Peng L, Wu TT, Tchieu JH, Feng J, Brown HJ, Feng J, Li X, Qi J,Deng H, Vivanco I, Mellinghoff IK, Jamieson C, Sun R.The Inhibition of PI3K-Akt Pathway Enhances Gamma-2 Herpesvirus Lytic Replication and Facilitates Reactivation from Latency.J Gen Virol. Feb;91(Pt 2):463-9, 2010. doi: 10.1099/vir.0.015073-0. Epub2009 Oct 28. 2009 Guo H., Wang LL, Peng L., Zhou ZH, andDeng H*.ORF33 of a gammaherpesvirus encodes a tegument protein essential for virion morphogenesis and egress.J Virol. Oct;83(20):10582-95, 2009. doi: 10.1128/JVI.00497-09. Epub 2009 Aug 5. Xu X, Lou Z, Ma Y, Chen X, Yang Z, Tong X, Zhao Q, Xu Y,Deng H,Bartlam M, and Rao Z.Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.PLoS One4(7):e6217, 2009. doi: 10.1371/journal.pone.0006217. Epub 2009 Jul 10. Liao HI, Olson CA, Hwang S,Deng H, Wong E, Baric RS, Roberts RW, Sun R.mRNA display design of fibronectin-based intrabodies that detect and inhibit severe acute respiratory syndrome coronavirus nucleocapsid protein.J Biol Chem. 2009 Jun 26;284(26):17512-20. doi: 10.1074/jbc.M901547200. Epub 2009 Apr13. Gong D, Qi J, Arumugaswami V, Sun R,Deng H*.Identification and functional characterization of the left origin of lytic replication of murine gammaherpesvirus-68.Virology. 2009 May 10; 387(2):285-95. doi: 10.1016/j.virol.2009.02.029. Epub 2009 Mar 12. Yang Z, Tang H, Huang H,Deng H*.RTA promoter demethylation and histone acetylation regulation ofmurine gammaherpesvirus 68 reactivation.PloS One4(2):e4556, 2009.doi:10.1371/journal.pone.0004556.Epub 2009 Feb 23. (Recommended by “Faculty of 1000 Biology”:http://www.f1000biology.com/article/id/1157092/evaluation) Di Bartolo DL, Hyjek E, Keller S, Guasparri I,Deng H, Sun R, Chadburn A, Knowles DM, Cesarman E.Role of defective Oct-2 and OCA-B expression in immunoglobulin production and KSHV lytic reactivation in primary effusion lymphoma.J Virol. 83: 4308-15, 2009.doi: 10.1128/JVI.02196-08.Epub 2009 Feb 18. Wu TT, Park T, Kim H, Tran T, Tong L, Martinez-Guzman D, Reyes N,Deng H, Sun R.ORF30 and ORF34 are essential for expression of late genes in murine gammaherpesvirus 68.J Virol. 83:2265-73,2009.doi: 10.1128/JVI.01785-08. Epub 2008 Dec 17. Arumugaswami V, Sitapara R, Hwang S, Song MJ, Ho TN, Su NQ, Sue EY, Kanagavel V, Xing F, Zhang X, Zhao M,Deng H, Wu TT, Kanagavel S, Zhang L, Dandekar S, Papp J, Sun R.High-resolution Functional Profiling of a Gammaherpesvirus RTA Locus in the Context of the Viral Genome.J Virol. 83:1811-22, 2009.doi: 10.1128/JVI.02302-08. Epub 2008 Dec 10. (*Co-Corresponding authors) |