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Wei Ji, Ph.D, Prof.
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Principal Investigator
Laboratory of Interdisciplinary Research, IBP
Research Interests: Single molecule localization microscopy and single molecule detection techniques.
Email: jiwei@ibp.ac.cn
Tel: 010-64888846
Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China
Chinese personal homepage
- Biography
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2001.09 - 2005.06 B.Sc. in Biomedical engineering, Huazhong University of Science and Technology, China
2005.09 - 2010.07 Ph.D. in Biophsics, Institute of Biophysics, CAS
2010.08 - 2011.12 Assistant professor, Institute of Biophysics, CAS
2012.01 - 2016.12 Associate professor, Institute of Biophysics, CAS
2017.01 - 2020.07 Professor, Institute of Biophysics, CAS
2020.07 - Professor, Principal Investigator, Institute of Biophysics, CAS
- Awards
- Membership in Academies & Societies
- Research Interests
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Try to develop new single molecule localization microscopy and single molecule detection (SMD) methods to solve problems that now faced by biomedical researchers.
- Grants
- Selected Publications
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1. Li W#, Lu J#, Xiao K#, Zhou M#, Li Y, Zhang X, Li Z, Gu L, Xu X, Guo Q*, Xu T*,Ji W*. Integrated multimodality microscope for accurate and efficient target-guided cryo-lamellae preparation.Nat. Methods.20, 268-275 (2023).
2. Wu W#, Luo S#, Fan C#, Yang T, Zhang S, Meng W, Xu T*,Ji W*, Gu L*. Tetra-color superresolution microscopy based on excitation spectral demixing.Light-Sci. Appl.12, 9 (2023).
3. Zhang R#, Gu L#, Chen W#, Tanaka N, Zhou Z, Xu H, Xu T,Ji W*, Liang X*, Meng W*. CAMSAP2/3 localize at microtubule intersections to regulate the spatial distribution of microtubules.J. Mol. Cell Biol.Accepted (2023).
4. Liu J#, Tang H#, Xu C, Zhou S, Zhu X, Li Y, Prézeau L, Xu T, Pin J*, Rondard P*,Ji W*, Liu J*. Biased signaling due to oligomerization of the G protein-coupled platelet-activating factor receptor.Nat. Commun.13, 6365 (2022).
5. Wang L#, Lu J#,Ji W*, Wan L*, Gu L*. Interferometrical single-molecule localization based on dynamic PSF engineering.Opt. Lett.47, 1770-1773 (2022).
6. Gu L,Ji W*. Recent progress on single-molecule localization microscopy.Biophys. Rep.7, 365-376(2021).
7. Gu L#, Li Y#, Zhang S#, Zhou M, Xue Y, Li W, Xu T*,Ji W*. Molecular-scale axial localization by repetitive optical selective exposure.Nat. Methods.18, 369-373(2021).
8. Gu L#, Li Y#, Zhang S#, Xue Y, Li W, Li D, Xu T*,Ji W*. Molecular resolution imaging by repetitive optical selective exposure.Nat. Methods.16, 1114-1118(2019).
9. Li Y, Xue Y, Xu X, Wang G, Liu Y, Wu H, Li W, Wang Y, Chen Z, Zhang W, Zhu Y,Ji W, Xu T, Liu L*, Chen Q*. A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.EMBO J.38(3), e98786(2018).
10. Xu X, Xue Y, Tian B, Feng F, Gu L, Li W,Ji W*, Xu T*. Ultra-stable super-resolution fluorescence cryo-microscopy for correlative light and electron cryo-microscopy.Sci. China Life Sci.61(11), 1312-1319(2018).
11. Zou W, Fu J, Zhang H, Du K, Huang W, Yu J, Li S, Fan Y, Baylis HA, Gao S, Xiao R,Ji W*, Kang L*, Xu T*. Decoding the intensity of sensory input by two glutamate receptors in one C. elegans interneuron.Nat. Commun.9(1), 4311(2018).
12. Lan X#, Fan C#,Ji W, Tian F, Xu T*, Gao Z*. Grafting voltage and pharmacological sensitivity in potassium channels.Cell Res. 26, 935-945 (2016).
13. Liu B#, Xue Y#, Zhao W#, Chen Y, Fan C, Gu L, Zhang Y, Zhang X, Sun L, Huang X, Ding W, Sun F,Ji W*, Xu T*. Three-dimensional super-resolution protein localization correlated with vitrified cellular context.Sci. Rep.5, 13017(2015).
14. Gu L#, Sheng Y#, Chen Y#, Chang H, Zhang Y, Lv P,Ji W*, Xu T*. High-density 3D single molecular analysis based on compressed sensing.Biophys J.106(11), 2443-9(2014).
15. Zhang Y#, Gu L#, Chang H#,Ji W#, Chen Y, Zhang M, Yang L, Liu B, Chen L*, Xu T*. Ultrafast, accurate, and robust localization of anisotropic dipoles.Protein & Cell. 4(8), 598-606(2013).
(From Wei Ji, April 13, 2023)