A complete list of publications can be foundHERE Zhang D, Kaige Y, Liu G, Song G, Luo J, Shi Y, Cheng E, Wu S, Jiang T, Lou Z, Gao N* andQin Y*(2016) (*corresponding author) EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome,Nat Struct Mol Biol. AbstractFull Text LinkFull Text PDF Zhang Y, Mandava CS, Cao W, Li X, Zhang D, Li N, Zhang Y, Zhang X,Qin Y, Mi K, Lei J*, Sanyal S*, Gao N* (2015) (*corresponding author) HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions,Nat Struct Mol Biol.22, 906–913. AbstractFull Text LinkFull Text PDF Zhang D, Kaige Y, Zhang Y, Liu G, Cao X, Song G, Xie Q*, Gao N*,Qin Y*(2015) (*corresponding author) New insights into the enzymatic role of EF-G in ribosome recycling,Nucleic Acids Res.1674–1683. AbstractFull Text LinkFull Text PDF Liu G, Zhang D, Song G, Li Z, Zhang D, Lyv Z, Aachenbach J, Dong J, Gong W, Zhao X, Nierhaus K H andQin Y*(2014) (*corresponding author) EF-G catalyzes tRNA translocation by disrupting interactions between decoding center and codon-anticodon duplex,Nat Struct Mol Biol.21, 817–824. AbstractFull Text LinkFull Text PDF Yang F, Gao Y, Li ZK, Chen LM, Xia Z, Xu T*,Qin Y*(2014) (*corresponding author) Mitochondrial EF4 links respiratory dysfunction and cytoplasmic translation in Caenorhabditis elegans.Biochim Biophys Acta.1674–1683. AbstractFull Text LinkFull Text PDF Yamamoto H#,Qin Y#, Achenhach J#, Li X, Kijek J, Kijek J, Sphan CMT and Nierhaus HK (2014) (#co-first author) EF-G and EF4: Translocation and back-translocation on the bacterial ribosome.Nat Rev Microbiol.12 (2) 89-100 (Invited review). AbstractFull Text LinkFull Text PDF Zhang D andQin Y*(2013) (*corresponding author) The Paradox of Elongation Factor 4: highly conserved yet of no physiological significance?Biochem J.452 (2), 173-181 (invited review). AbstractFull Text LinkFull Text PDF Zhang D, Liu G, Xue J, Lou J, Nierhaus K H, Gong W* andQin Y*(2012) (*corresponding author) Common chaperone activity in the G-domain of trGTPase protects L11–L12 interaction on the ribosome,Nucleic Acids Res.40 (21) 10851-10865. AbstractFull Text LinkFull Text PDF Wang L, Yang F, Zhang D, Chen Z, Xu R, Nierhaus K H, Gong W andQin Y*(2012) (*corresponding author) A conserved proline switch on the ribosome facilitates the recruitment and binding of trGTPases,Nat Struct Mol Biol.19(4)403-410. AbstractFull Text LinkFull Text PDF Di Giacco V#, Marquez V#,Qin Y#, Pech M, Triana-Alonso FJ, Wilson DN, Nierhaus KH (2008) (#co-first author). Shine-dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the aug.Proc Natl Acad Sci U S A.105(31):10715-10720. AbstractFull Text LinkFull Text PDF Connell SR#, Topf M#,Qin Y#, Wilson DN, Mielke T, Fucini P, Nierhaus KH, Spahn CM (2008) (#co-first author) A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation.Nat Struct Mol Biol.15(9):910-915. AbstractFull Text LinkFull Text PDF Qin Y, Polacek N, Vesper O, Staub E, Einfeldt E, Wilson DN, Nierhaus KH* (2006) (*corresponding author) The highly conserved lepa is a ribosomal elongation factor that back-translocates the ribosome.Cell.127(4):721-733. AbstractFull Text LinkFull Text PDF |