高利增课题组

简 历：

　　1997-2001 吉林大学生命科学学院，学士

　　2001-2004 吉林大学生命科学学院，硕士

　　2004-2008 中国科学院生物物理研究所，博士

　　2009-2014 美国费城儿童医院小儿科血液学系，博士后

　　2015-2016 美国费城儿童医院小儿科血液学系，助理研究员

　　2016-2020 扬州大学医学院，讲师

　　2020-至今 中国科学院生物物理研究所，助理研究员

获奖及荣誉：

　　2007年 北京市科学技术进步奖，三等奖，抑制血管新生是抗肿瘤免疫反应的主要效应机制（第六）

社会任职：

研究方向：

　　（1）纳米酶抗菌和抗病毒作用机制研究；

　　（2）纳米酶核酸递送和抗肿瘤作用机制研究。

承担项目情况：

代表论著：

　　1.Qian Wang#,Jing Jiang, and Lizeng Gao*. Nanozyme-based medicine for enzymatic therapy: progress and challenges,Biomedical Materials, 2021, 16 (5): 042002.

　　2.Xinyu Shen #, Ruonan Ma #, Yixin Huang #, Lei Chen #, Zhuobin Xu, Dandan Li, Xiangqin Meng, Kelong Fan, Juqun Xi, Xiyun Yan, Hyun Koo, Yili Yang,Jing Jiang, and Lizeng Gao*, Nano-decocted ferrvbous polysulfide coordinates ferroptosis-like death in bacteria for anti-infection therapy,Nano Today, 2020 , 35: 100981.

　　3.Tao Qin#, Shang Ma #, Xinyu Miao, Yan Tang, Dandan Huangfu, Jinyuan Wang,Jing Jiang, Nuo Xu, Yuncong Yin, Sujuan Chen, Xiufan Liu, Yinyan Yin*, Daxin Peng*, and Lizeng Gao*, Mucosal Vaccination for Influenza Protection Enhanced by Catalytic Immune-Adjuvant ,Advanced Science, 2020, 7(1 8): 2000771.

　　4.Yunhao Gu#, Yixin Huang, Zhiyue Qiu, Zhuobin Xu, Dandan Li, Lei Chen,Jing Jiang, and Lizeng Gao*. Vitamin B2 functionalized iron oxide nanozymes for mouth ulcer healing.SCIENCE CHINA Life Science, 2020，63(1):68-79

　　5.Joanna Balcerek#,Jing Jiang#, Yang Li, Qinqin Jiang, Nicholas Holdreith, Brijendra Singh, Vemika Chandra, Kaosheng Lv, Jian-gang Ren, Krasimira Rozenova, Weihua Li, Roger A. Greenberg, and Wei Tong*. Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficiency Fanconi anemia.Nature Communications, 2018, 9: 3915.

　　6.Zhuobin Xu#, Zhiyue Qiu#, Qi Liu#, Yixin Huang, Dandan Li, Xinggui Shen, Kelong Fan, Juqun Xi, Yunhao Gu, Yan Tang,Jing Jiang, Jialei Xu, Jinzhi He, Xingfa Gao, Yuan Liu, Hyun Koo, Xiyun Yan, and Lizeng Gao*. Converting organosulfur compounds to inorganic polysulfides againist resistant bacterial infections.Nature Communications, 2018, 9: 3713

　　7.Kaosheng Lv#,Jing Jiang, Ryan Donaghy, Christopher R. Riling, Ying Cheng, Vemika Chandra, Krasimira Rozenova, Wei An, Bhopal C. Mohapatra, Benjamin T. Goetz, Vinodh Pillai, Xu Han, Emily A. Todd, Grace R. Jeschke, Wallace Y. Langdon, Suresh Kumar, Elizabeth O. Hexner, Hamid Band, and Wei Tong*. CBL family E3 ubiquitin ligase control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.Genes & development. 2017; 31 (10):1007-1023.

　　8.Krasimira Rozenova#,Jing Jiang, Ryan Donaghy, Bernadette Aressy, Roger A. Greenberg, and Wei Tong*. MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling.Blood, 2015, 125 (11): 1730-1738.

　　9.Michele P Lambert#,Jing Jiang, Vandana Batra, Chao Wu, and Wei Tong*. A novel mutation in MPL (Y252H) results in increased thrombopoietin sensitivity in essential thrombocythemia.American Journal of Hematology. 2012; 87(5):532-534.

　　10.Jing Jiang#, Joanna Balcerek#, Krasimira Rozenova, Ying Cheng, Alexey Bersenev, Chao Wu, Yiwen Song, and Wei Tong*. 14-3-3 regulates the Lnk/JAK2 pathway in mouse hematopoietic stem and progenitor cells.The Journal of Clinical Investigation, 2012; 122(6): 2079-2091.

　　11.Duonan Yu#, Camila O. dos Santos#, Guowei Zhao#,Jing Jiang, Julio D. Amigo, Eugene Khandros, Louis C. Dore, Yu Yao, Janine D’Souza, Zhe Zhang, Saghi Ghaffari, John Choi, Sherree Friend, Wei Tong, Jordan S. Orange, Barry H. Paw and Mitchell J. Weiss*. miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta.Genes & development. 2010; 24 (15):1620-33

　　12.Jing Jiang#, Zibing Wang#, Zhiguang Li, Jinhua Zhang, Chunhui Wang, Xia Xu and Zhihai Qin*. Early exposure of high dose interleukin-4 to tumor stroma reverses myeloid cell-mediated T cell suppression.Gene therapy, 2010; 17(8):991-999