生物物理所研究生会(2007)第十次学术沙龙活动有幸请来鲁白教授为大家做一场报告并与大家交流。望有兴趣的同学踊跃参与。

　　报告人：鲁白

　　主持人：赫荣乔

　　地点：生物物理所图书馆报告厅

　　时间：2008年3月26日（周三）下午2:00-4:00

　　鲁白教授简介：

　　1996年 至今，美国国立儿童健康与人类发育中心研究员，

　　研究方向为：神经元的神经营养性调控机理及其意义;

　　1993-1996，在罗氏分子生物学研究中心开展研究工作；

　　1993年以前，康奈尔大学医学院获博士学位，之后于

　　洛克菲勒大学做博士后工作。

　　Dr. Lu received his Ph.D. from Cornell University Medical College. He did his postdoctoral work at Rockefeller University with Paul Greengard and Mu-ming Poo on molecular mechanism of synaptic transmission and development, using the Xenopus neuromuscular synapses as a model system. In 1993, he became a faculty member at Roche Institute of Molecular Biology, where he began studying the role of neurotrophins in synapse development and plasticity. He joined NICHD as an Investigator in 1996. His laboratory investigates the mechanisms underlying neurotrophic regulation of synapses, and their functional significance.

　　代表性论文：

　　1. Ama"Zinc" Link between TrkB Transactivation and Synaptic Plasticity. Neuron. 2008.

　　2. Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science. 2004.

　　3. Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell. 2007.

　　4. Neurotrophin 3 induces structural and functional modification of synapses through distinct molecular mechanisms. Cell Biol. 2006.

　　http://neuroscience.nih.gov/Lab.asp?Org_ID=275